The frequently occurring reported exonic SNP (rs41314153) was located in exon 6 of the ABCD1 gene 1548G/A (Leu516Leu) with MAF (minor allele frequency) “T” 16/84 (19.04%) in healthy normal controls and 3/20 (15%) in adrenoleukodystrophy patients. This evidence concerns the gene ABCD1 and adrenoleukodystrophy.