UDP-glucuronosyltransferase 1–2 Precursor (UDPGT)/Ugt1a10) and the mitochondrial import inner membrane translocase subunit (Tim22) gene were reduced in all three colon cancers; as was the ALEX (Gnas) gene in both breast cancer studies. The gene discussed is UGT1A1; the disease is malignant colon neoplasm.