Because p-HSP27(Ser15) and HER2 showed prognostic value to the clinical outcome for oesophageal adenocarcinoma patients, we performed a second hierarchical cluster analysis of the investigated members of the HSP27 group (HSP27; p-HSP27(Ser15); p-HSP27(Ser78); p-HSP27(Ser82)) and the HER family proteins (EGFR, HER2, HER3, HER4, pEGFR, p-HER2, p-HER3). Here, ERBB3 is linked to esophageal adenocarcinoma.