K562 chronic myeloid leukemia is the CML in blast crisis, and the cells carry the Philadelphia chromosome with a BCR-ABL b3-a2 fusion gene (Hehlman 2007).In the past, the treatment was done with antimetabolites (cytarabine, hydroxyurea), alkylating agents, interferon alpha 2b, and steroids, but these drugs have been replaced by Gleevec. The gene discussed is IFNA2; the disease is chronic myelogenous leukemia, BCR-ABL1 positive.