IGHE and allergic bronchopulmonary aspergillosis: Recently, in 2003, Saxena et al. [73] reported that ABPA patients with polymorphisms (ala91pro and arg94arg) in the collagen region of pulmonary surfactant protein A2 (SP-A2) had more elevated total IgE levels and higher percentages of eosinophilia than observed in those patients who lacked the SNPs (Table 1).