Heishi et al., analyzed PBMCs in atopic dermatitis patients and found 4 transcripts, (IFN-γ, TRAIL, ISGF-3, and defensin-1), through screening GeneChip and confirmatory PCR, that were significantly different in atopic dermatitis patients compared to healthy controls [27]. The gene discussed is TNFSF10; the disease is atopic eczema.