TNF and melanoma: Since UV radiation generates inflammation and oxidative stress in melanocytes which may lead to its transformation into melanoma, this study investigated the effect of the CO2-SFE mussel oil and 5β-scymnol in relation to α-tocopherol on the release of the pro-inflammatory cytokine TNF-α via the p38 MAPK pathway in UVB-irradiated human melanocyte-derived cells.