Beside lung failure, the first 24 hours after admission were marked by the development of circulatory shock requiring norepinephrine, acute renal failure and acute liver failure with cell necrosis: aspartate amino transferase (ASAT) = 1340 IU/L, alanine aminotransferase (ALAT) = 600 IU/L, alkaline phosphatase (AP) = 104 IU/L, gamma-glutamyl transpeptidase (γ-GT) = 80 UI/L, total bilirubin = 60 μmol/L, prothrombine time (PTT) = 40%, platelet count = 147 G/L. This evidence concerns the gene DHCR7-DT and acute liver failure.