Immunohistochemical staining of liver sections for GRP78 and CHOP in mice given ALIOS diet and liraglutide suggest that GLP-1 analogs impart a strong affect in liver; though reduction in hepatic steatosis could as well be a result of whole body response to liraglutide, since GLP-1 receptors are present in other organs also. This evidence concerns the gene GCG and fatty liver disease.