The implicated chromosome 9p21 locus associated with myocardial infarction, the 4q25 locus near the PITX2 and variants in the ZFHX3 were included in our meta-analysis and summary statistics for these implicated loci may be found in the Table S2, although the small effect sizes in original reports from studies with larger sample sizes caused detection of these effects on a genome-wide scale to be impossible. Here, PITX2 is linked to myocardial infarction.