Tumor doubling times were increased in a somewhat dose-dependent manner, being 3.14 ± 0.23 days with vehicle, 3.55 ± 0.31 days with +10 ng EFEMP1, and 4.24 ± 0.42 days in the +20 ng EFEMP1 (P = 0.046). The gene discussed is EFEMP1; the disease is neoplasm.