RT-PCR showed that there was a lack of MACC1 expression in the normal liver cell line L-02, while all of four hepatoma cell lines (SMMC-7721, Hep-G2, MHCC-97L and MHCC-97H) expressed MACC1 mRNA (Figure 1A). This evidence concerns the gene MACC1 and hepatocellular carcinoma.