BIRC2 and neoplasm: However, the overall 5-year survival rate of patients with cIAP2-negative tumours was significantly higher than that of patients with cIAP2-positive tumours (81.9% versus 40.1% P=0.0008; Figure 5B), whereas the cIAP1 and XIAP expression status were not associated with the overall 5-year survival rate of OSCC patients (Figure 5A and C).