Many of the genes that were upregulated in both FSHD myoblasts and myotubes were related to the response to cell stress, such as GSTP1, HSP90AA1 HSP90AB1 HSPA1A, HSPC152, and DNAJC4 (See Additional File 8 for gene lists). The gene discussed is HSP90AB1; the disease is facioscapulohumeral muscular dystrophy.