EGFR and non-small cell lung carcinoma: In order to shed light on the clinical impact of the multiple interconnections and crosstalk between these components of the NF-κB and the EGFR pathways, we examined the expression of eleven genes (Figure 1) and the mutational status of two genes (Figure 1) and correlated our findings with outcomes in metastatic NSCLC patients in whom EGFR and K-ras genetic status had previously been determined.