PGLYRP4 and atopic eczema: Later (day 20), atopic dermatitis-sensitive mice (Pglyrp3−/−, Pglyrp4−/−, and Pglyrp2−/−Pglyrp3−/− mice) had four genes characteristic of Th17 cells (Cxcl1, Cxcl5, IL17a, IL22) and one gene characteristic of several cell types (Ccl2) activated more than three-fold higher in Pglyrp-deficient than in WT mice (Figure 7A and Figure S4).