Prolonged treatment with oxazolone in the atopic dermatitis model induced increases in mRNA of several cell types in WT mice, and especially mature B cells, CD8+ T cells, monocytes, PMNs, and mast cells, as well as changes associated with de-differentiation, proliferation, and activation of keratinocytes, which are all expected changes consistent with the atopic dermatitis model (Figure 6A and Figure S1). Here, CD8A is linked to atopic eczema.