GLIS3 and type 2 diabetes mellitus: In addition to the TCF7L2 and SLC30A8 variants, which have previously demonstrated association with type 2 diabetes in the UKADS/DGP study populations [3], [6], alleles of the ADCY5 rs11708067 (OR = 1.23 [95% CI: 1.09, 1.39] p = 9.10×10−4) and GLIS3 rs7034200 (OR = 1.16 [95% CI: 1.05, 1.29] p = 3.49×10−3) SNPs conferred risk of the disease in this study (Figure 2).