CDH1 and prostate carcinoma: It is clear from immunohistochemical studies that low-grade prostate carcinomas maintain cell cohesion through components of the tight junction including Z01, claudins and occludin (see Martin and Jiang [47]), zonula adherens (E-cadherin, B-catenin, desmosomes) [46], as well as gap junction proteins and apical adhesion molecules such as CEACAM1 (carcinoembryonic antigen-related cell adhesion molecule 1) [54].