We then measured the level of XMRV DNA in the blood from cohort 2 which included 50 healthy persons and 97 patients with chronic inflammatory diseases including 30 with rheumatoid arthritis, 20 with Behcet's disease, 10 with systemic lupus erythematosus, and 9 with cryopyrin-associated periodic syndromes (Table 2). Here, NLRP3 is linked to systemic lupus erythematosus.