An increase of about 3-fold was observed at the protein level, while confocal images did not show significant difference, as compared to Caco-2 (Figure 2D), since it is known that some cancer epithelial cells abnormally express N-cadherin which has been shown to promote motility and invasion [26,27], N-cadherin expression was examined (Figure 2E). This evidence concerns the gene CDH2 and cancer.