TF and atrial fibrillation: TF hypercoagulability driving the coagulation-inflammation-thrombosis circuit (Figure 3) readily extends its diverse consequences to cardiovascular complications and vascular diseases [219] including arrhythmias [58], arterial hypertension [220], hypertrophy [221], ACS [222, 223], andatrial fibrillation (AF) [224], TF hypercoagulability with elevated proinflammatory cytokines (Figure 2) could in part well contribute to atherosclerosis known as chronic inflammatory disease [217].