SLC12A1 and Bartter syndrome: Mutations of SLC12A1 gene have been associated with the most typical form of antenatal Bartter syndrome featuring early onset of polyhydramnios, neonatal polyuria, and dehydration requiring massive amount of water and sodium supplementation in the first days of life, detectable nephrocalcinosis on renal ultrasound within the first month, and high plasma level of renin and secondary hypokalemic alkalosis following the first days of life [46, 47].