In parallel, Cy3-labeled miR-223 from IL-4-activated macrophages was more efficiently transported into SKBR3 breast cancer cells (13.36 ± 3.52%) than the labeled miR-223 from unactivated macrophages (7.85 ± 2.84%) (Additional file 5 Figure S4). This evidence concerns the gene IL4 and breast carcinoma.