SLC67A1 and glioma: Collectively, our data demonstrates that SLC22A18 promoter methylation contributes to the downregulation of SLC22A18 in gliomas and reduced SLC22A18 expression plays a role in the molecular pathogenesis of glioma, as SLC22A18 overexpression can effectively inhibit U251 glioma cell growth and adhesion in vitro and tumor growth in vivo.