This speculation is strengthened by the findings of previous reports showing that exogenous 14-3-3γ leads to polyploidization in H322 lung cancer cells [25], that the overexpression of 14-3-3γ in a lung cancer cell line promotes re-entry into S phase [26], and that the overexpression of 14-3-3ζ induces the proliferation of breast cancer cells [28]. Here, YWHAG is linked to lung cancer.