As a conclusion, our results identified a subset of DCs that (i) express the markers of moDCs, (ii) are newly generated during in vivo candidiasis in a TLR2 dependent manner, (iii) are generated in vitro from Lin− progenitors cells in response to C. albicans by a TLR2/MyD88 and Dectin-1 dependent mechanism, (iv) are able to secrete TNF-α, and (v) have fungicidal activity. This evidence concerns the gene MYD88 and Candidiasis, Invasive.