Because of the increased susceptibility of TLR2−/− mice to systemic candidiasis [20] the low-virulence PCA2 strain was chosen for the infection, in order to avoid mice mortality and severe differences in fungal burden between control and knockout mice; this strain has been widely used to study the immune response to C. albicans infections [21], [22], [23], [24]. Here, TLR2 is linked to infection.