IRF3 and glycogen storage disease VI: IRF3 rs2304207 was significantly associated with symptomatic WNV disease (OR = 0.54 [95% confidence interval (CI) 0.39–0.74]; p = 0.035) under a dominant genotypic model (Table 3) with the GC and GG genotypes found significantly more often in asymptomatic WNV-positive controls than in WNV symptomatic cases.