Consistent with the flow cytometric analysis, we observed that FoxP3+ cells preferentially accumulated in tumor tissue (7.3±0.6/hpf) rather than in non-tumor tissue (2.8±0.4/hpf) or normal control livers (0.4±0.1/hpf) (both P<0.001 for T vs. nT and T vs. NC; Figure 2c, d). The gene discussed is FOXP3; the disease is neoplasm.