For example, glioblastoma CSCs are very sensitive to temozolomide [52] or blocking L1CAM signaling [53]; ovarian CSCs in the side population are sensitive to TNFα [54]; colon CSCs can be efficiently killed by γδ T lymphocytes [55]; and breast CSCs are selectively targeted by salinomycin [56], metformin [57], or conventional chemodrugs [58]. The gene discussed is TNF; the disease is glioblastoma.