The percentages of nTreg and mTreg cells within CD4+ T cells were also significantly lower in CHF patients than in age-matched non-CHF subjects (non-CHF vs. CHF patients: nTreg: 1.17±0.41% vs. 0.59±0.31%, p<0.01; mTreg: 3.27±0.92% vs. 2.02±0.65%, p<0.01; Figure 1D). This evidence concerns the gene CD4 and congestive heart failure.