RM1-IL18 tumors generated in immunocompromised RAG1−/− mice (from Fig. 4 A) from the Ctrl treatment group had greater infiltration of macrophages and neutrophils compared to IL-18-neutralized tumors (Figure S3 A–D) showing tumor infiltration of macrophages and neutrophils in RAG1−/− mice). The gene discussed is TIPARP; the disease is neoplasm.