SOCS3 and lymphangioleiomyomatosis: Further confirmation about the role of SOCS3 in the generation of host protective immune responses in Ara-LAM treated infected sets was done by SOCS3 silencing which was suggestive of SOCS3 hindrance in Ara-LAM mediated induction of proinflammatory response (figure 6, 7A, 7B, 7C).