ITGAM and infection: Figure 4 A shows representative dot plots of lung cells from the isotype control, reference CIP 108297 and the outbreak M. massiliense CRM-0019 strain after 30 days of infection in mice primarily gated on CD11b+ macrophages cells expression of IL-12. As shown in Figure 4 B and C, macrophages and dendritic cells from the CRM-0019-infected mice showed reduced numbers of lung and spleen IL-12 and TNFα producing macrophage and dendritic cells compared to the reference strain CIP 108297.