TNFRSF10B and diffuse large B-cell lymphoma: As expected, we found that DLBCL cells that were transfected with scrambled non-specific siRNA showed a synergistic apoptotic response to the combination treatment; however, in those cells that were transfected with siRNA against DR5, there was a diminished apoptotic response following combination treatment of Resveratrol and TRAIL at sub-toxic doses (Figure 6C and D).