ERBB2 and gastric cancer: Recently, the Trastuzumab for Gastric Cancer (ToGA) trial noted that the addition of trastuzumab to chemotherapy led to a statistically significant improvement in progression-free survival (PFS) and overall survival (OS) of the approximately 20% of patients with disseminated gastric and gastroesophageal (GE) junction tumors overexpressing HER2 [7].