LEP and Insulin resistance: After correction for possible confounding parameters, including age, BH, BW, abdominal visceral fat area, systolic and diastolic blood pressure (BP), levels of total cholesterol, high-density lipoprotein cholesterol, triglyceride, HbA1c, Homeostatic Model Assessment as an index of insulin resistance (HOMA-R), hs-CRP, and white blood cell count, thigh muscle CSA was found to be independently, significantly, and negatively related to plasma leptin levels in both men and women.