IGHG3 and neoplasm: Single MAb C595 only partially inhibited the growth of OVCAR-3 tumors, as evidenced by tumor weight of 380±80 mg in LD (5 mg/kg) and 260±76 mg in HD (150 mg/kg) versus 560±77 mg in mice receiving negative MAb IgG3 control (15 mg/kg) (P<0.05), respectively while single DTX obviously inhibited the growth of OVCAR-3 tumors, as evidenced by tumor weight of 230±66 mg in LD (5 mg/kg) and 75±14 mg in HD (10 mg/kg) versus 540±96 mg in mice receiving the same volume of HPMC (P<0.05), respectively (Fig. 2B).