Lentiviral expression of siRNA against mda-7/IL-24 in ovarian cancer cells demonstrated that knockdown of mda-7/IL-24 reduces diclofenac-induced GADD45 α and γ gene expression indicating that GADD45α and γ induction is at least partially dependent on mda-7/IL-24 expression (Figure S3c). This evidence concerns the gene GADD45A and ovarian cancer.