In line with the concept that MDR cells can develop stem-like properties and be identified as cancer stem cells, different studies have shown that cell stressors such as hypoxia, which are efficient in inducing cancer aggression and MDR phenotypes, also induce stem-like properties in cancer cells such as the expression of stem cell factor (SCF) [3], [4], [9], [19], [20]. The gene discussed is KITLG; the disease is cancer.