TERT and nasopharyngeal carcinoma: Additionally, latent membrane protein (LMP)1, which is the principal oncoprotein encoded by EBV, was able to induce the direct binding of TERT to nuclear factor kappa B (NF-κB) p65 in NPC cells, then lead to translocation of both proteins from the cytoplasm to the nucleus, and subsequent activation of telomerase and cell immortalization [16].