The novel putative intestinal and pancreatic stem cell marker DCAMKL-1 [5-7], a microtubule-associated kinase is upregulated in colorectal and pancreatic cancers and plays a functional role in tumorigenesis through regulation of the tumor suppressor microRNAs (let-7a, miR-200a and miR-144) and their downstream targets such as c-Myc, KRAS, ZEB1, ZEB2 and Notch-1 [8,9]. Here, NOTCH1 is linked to neoplasm.