In the first experiment, we evaluated inhibition of cell free HIV-1IIIB virus infection by monoclonal antibody to HIV-1 gp41 (126-7), HIV-1 gp120 antiserum (PB1), HIV-1 gp120 antiserum (PB1 sub 2), HIV-1 gp120 monoclonal antibody (F425B4e8), and compared that with HIV-1 inhibition by AgNPs alone and relevant NABs + AgNPs cocktail. The gene discussed is ITIH4; the disease is viral infectious disease.