Similar results were reported by Paschka et al. [26], who evaluated 805 adults with AML enrolled in the German-Austrian AML study group, and found IDH mutations in 129 patients (16.0%), IDH1 mutations in 61 patients (7.6%) and IDH2 mutations in 70 patients (8.7%). The gene discussed is IDH1; the disease is acute myeloid leukemia.