In our cohort, among 52 Moroccan Jewish individuals with hearing loss, not closely related to each other by self-report, 10 were homozygous for CX26 c.35delG, 10 were homozygous for TMC1 p.S647P, 6 were compound heterozygous for TMC1 p.S647P and p.R604X, and 9 were heterozygous for TMC1 p.S647P. Here, TMC1 is linked to hearing loss disorder.