Further, treatment of dissociated GBM cells with a monoclonal antibody for pan-CD44 (clone IM7; ABcam), which is widely used to block the pan-CD44 signals in vitro[37], [38] resulted in abraded neurosphere formation in the CD44high samples (GBM107 and 1600) (Figure S. 3A, left panel). Here, CD44 is linked to glioblastoma.