MYBPC3 and familial dilated cardiomyopathy: A common polymorphic intronic deletion of 25-base- pair in MYBPC3 at the 3′ region of the gene [19] has been recently reported to be associated with DCM and HCM in populations of Southeast Asia.[20] The deletion in intron 32 causes skipping of the downstream exon 33 and results in incorporation of mis-sense amino acids at C-terminal region of the protein.[19], [20] The 25-bp deletion is present in 2–6% of individuals in Indian populations and high incidence of cardiac diseases has been partly attributed to the existence of this polymorphism.