Earlier, another UK based study did not observe differences in incidence of LVSD but reported that majority of patients originating from Indian subcontinent had CAD as underlying cause of LVSD.[21] As MYBPC3 25 bp deletion is mainly confined to Southeast Asia,[20] it is possible that some of the differences in two groups (Southeast Asians and Whites) might be associated with the common MYBPC3 25 bp deletion. This evidence concerns the gene MYBPC3 and coronary artery disorder.