MYBPC3 and familial dilated cardiomyopathy: Earlier genetic studies have correlated LVD with dilated cardiomyopathy (DCM).[2] Mutations in several genes including those encoding sarcomeric proteins such as myosin heavy polypeptide (MYH7), cardiac troponin I (TNNI3),[3] cardiac myosin binding protein C (MYBPC3)[4] have been identified in DCM.[5], [6], [7]