Another gene that showed one of the most significant fold-decreases during neuronal differentiation is FZD5 (frizzled 5 precursor), a receptor for WNT5A, which is particularly interesting in the context of neuropsychiatric disorders because signaling through canonical WNT-mediated signal transduction appears to be involved in SZ and BD in subgroups of patients [1], [47]–[50]. Here, FZD5 is linked to Behcet disease.