Immunohistochemically, the carcinoma with hepatoid features was diffusely stained for α fetoprotein (AFP), HepPar-1 (Figure 3a) and Hepatocyte-cell antibodies, but not for Keratin7, whereas the well-differentiated adenocarcinoma was immunoreactive for Keratin7 but not for AFP or Hepatocyte-cell. This evidence concerns the gene AFP and carcinoma.