To derive a more precise estimation, we therefore meta-analyzed three eNOS widely-evaluated polymorphisms, G894T (rs1799983) in exon 7, 4b/a (an insertion-deletion with 4a denoting four tandem 27-bp repeats and 4b five repeats) in intron 4, T−786C (rs2070744) in promoter region, in association with hypertension from the English and Chinese-published literature, while addressing between-study heterogeneity and publication bias. This evidence concerns the gene NOS3 and hypertensive disorder.