The use of EAT-2 to augment CSP specific functional CD8+ T cells may be of greatest importance in killing Plasmodium infected hepatocytes, as these types of responses are not only positively correlated with protective capability, but also may outweigh the need for induction of malaria antigen specific antibody responses [4], [5], [54], [55]. Here, DNAJC5 is linked to malaria.